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5–four ?mol/L variety,[156][157] the focus of serotonin in synaptic vesicles was measured at 270 mM.[182] Following vesicular launch, the ensuing focus of serotonin inside the synaptic cleft, to which serotonin receptors are exposed, is approximated for being about 300 ?mol/L. Thus, whilst in vitro receptor binding affinities, efficacies, and n
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